Oxycodone in the Opioid Epidemic: High Liking, Wanting, and Abuse Liability PMC
Oral oxycodone has better bioavailability (about 60–90%) than morphine and with the same unbound concentrations of oxycodone and morphine in the blood, unbound oxycodone in the brain is as much as six times higher than morphine (Boström et al. 2008). Preclinical research reports differences in potency, where oxycodone was 2 to 4 times more potent […]
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